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A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.
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Donor antigen-specific regulatory T-cell function affects outcome in kidney transplant recipients.

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Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients.

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The following review focuses on the nephrotoxic actions of tacrolimus with particular reference to the associated histopathological changes seen in the allograft kidney.

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Gayol P1, Dry N1, Bayle E1, Khalil F1, Torcatoriu A1, Moceanu C1, Meyer N2, Flesch F3, Lessinger J4, Kopferschmitt J1 1 Emergency Department, Strasbourg University Hospital NHC (Nouvel Hôpital Civil), Strasbourg, France; 2Department of Biostatistics, Strasbourg, France; 3 Strasbourg Poison Center, Strasbourg, France; 4Biological Analysis Laboratory, Strasbourg University Hospital NHC (Nouvel Hôpital Civil), Strasbourg, France Aims: Paracetamol (APAP) is the most common drug of intentional overdose in the United Kingdom and the most common cause of acute liver failure.

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Azathioprine use in transplantation has been widely replaced by mycophenolate mofetil in North America.

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Probe reactions were chenodeoxycholic acid 24-acyl-glucuronidation (UGT1A3), mycophenolic acid 7-O-glucuronidation (UGT1A9) and acyl-glucuronidation (UGT2B7).

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Applied by us quantitative enantioselective method for MIA metabolism, tested in the pilot study, could be applied for further studies on the role of enantioselective MIA metabolism in patients treated with this antidepressive drug and may contribute to better understanding of therapeutic effect of S-MIA enantiomer during mianserin treatment.

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Since polyoxyethylated castor oil, a solubilizer used in the injective formulation of both cyclosporine and tacrolimus, is considered to be responsible for the reaction, she was given oral capsules of cyclosporine (Sandimmun) in which polyoxyethylated castor oil was not contained.

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One fourth of patients with treated status epilepticus who appear to be seizure-free continue to have seizure activity that is only detectable with EEG.

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The ratios of geometric least squares means and 90% confidence intervals were calculated for AUC 24, C max, and C min for the following 3 comparisons: day 14 LCP-Tacro versus day 7 Prograf, day 21 LCP-Tacro versus day 7 Prograf, and day 21 LCP-Tacro versus day 14 LCP-Tacro.

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Results: Baseline characteristics, including time after transplantation, age, sex, weight, hemoglobin, creatinine and albumin, did not differ between the groups of transplant recipients.

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